Objective: In this study, we aimed to inform people that acne can be improved with Osuyu-tang (OSYT) based on the Shanghanlun disease pattern identification diagnostic system (DPIDS).

Methods: We evaluated the progress of symptoms, patient compliance, and presence of side effects after the patient took OSYT. The progress of acne treatment was evaluated using the Korean Acne Grading System (KAGS), visual findings, and patient statements.

Results: According to the DPIDS, the patient was diagnosed with provision 309 of soyinbing. After administration of OSYTfor 50 days, KAGS decreased from grade 3 to grade 1. Cold hands and feet improved significantly.

Conclusions: Through this case study, we showed the possibility of the clinical interpretation and application of OSYT and suggested further case studies in the future.

Key words: Soyinbing, Osuyu-tang, acne, disease pattern identification diagnostic system based on Shanghanlun provisions (DPIDS), Shanghanlun