Objective : This study aimed to report the improvement of two patients with headache not otherwise classified treated using Saengkangsasim-tang based on the disease pattern identification diagnostic system (DPIDS) based on the Shanghanlun provisions.

Methods : Two patients with headache not otherwise classified were treated using Saengkangsasim-tang according to Shanghanlun provisions, and the effect was also compared with Soshiho-tang. The results were evaluated using a numerical rating scale (NRS) and the Korea Headache Impact Test-6 (KHIT-6). In addition, new clinical implications for the interpretation of Shanghanlun provision 157 were reviewed.

Results : As a result of analyzing the results of the two cases, treatment with Sosiho-tang was ineffective but improved when using Saengkangsasim-tang. After administration of Saengkangsasim-tang, all headaches decreased to the point where they were not uncomfortable in everyday life.

Conclusions : The administration of Saengkangsasim-tang to patients with headache diagnosed according to Shanghanlun provision 157, suggesting that it is clinically effective when applied according to the definitions provided by the Shanghanlun provisions.

Key words : Saengkangsasim-tang, headache not otherwise classified, disease pattern identification diagnostic system by Shanghanlun provisions (DPIDS), Shanghanlun