Objectives: We aimed to confirm the safety and effectiveness of the decoction type of Sibjo-tang, which is a named powder type purgative. In addition, we objected to check whether the '發作' of 『Shanghanlun』 can be interpreted as the same meaning as the 'seizure' in English. By confirming these, we intended to lead the progress in the application of the Sibjo-tang, and to expand the clinical application fields of the 152th provision and Sibjo-tang.
Methods: We analyzed the medical records of the patients who have visited Apgujeongjeongin Oriental Clinic and Almyeon Oriental Clinic for seizure. And we confirmed the side effects of patients who took Sibjo-tang for a long period of time. Sibjo-tang was prepared as a hot water extracts by using 5g each of Euphorbiae Pekinensis Radix, Eurphobiae Kansui Radix, Genkwae Flos, and and 15g of Zizyphi Fructus. The “seizure” recorded in the 152th provision was interpreted through the analysis of the shape of Oracle bone scripts. The seizure frequency of patients diagnosed with epilepsy after taking Sibjo-tang was compared, and other symptoms and psychosocial conditions associated with seizures at the first episode were analyzed.
Results: No side effects were found in 7 patients who took Sibjo-tang for 16.57 ± 14.10 months. Seizures were eliminated in 6 cases while taking Sibjo-tang and significantly decreased in 1 case. In 7 cases, frequent indigestion (in 7 cases), easy exhaustion (in 5 cases), and inferiority complex (in 5 cases) were found as accompanying pathogenic conditions. The “seizure” in 152th provision was interpreted as ‘a state of being stabbed by a sharp substance in clothes’, confirming a deep connection with seizures of epilepsy.
Conclusions: The results suggest that the decoction type application of Sibjo-tang has safety and efficacy. In addition, it was confirmed the necessity of conducting an advanced study on epileptic seizures accompanied by frequent indigestion using Sibjo-tang.
Keywords : Shanghanlun, 發作, seizure, epilepsy, Sibjo-tang, a disease pattern identification diagnostic system