Original Article

수치에 의한 부자류 식물의 아코니틴 함량의 변화에 대한 연구

Effects of Various Processing Methods on the Contents of Aconitine in the Aconitum Plants

2010 Vol. 2 No. 1
동신대학교 한의과대학 본초학교실1, 전남한방산업진흥원2, 동우당제약3
Dae-Won Mun1#, Chae-hyun Kim1*, Jong-Gil Jeong1, Hyun- Woo Cho2, Ji-Hoon Ryu2,
Jung-Hee Cho2, Dae-Sang Kim3
Department of Herbology, College of Oriental Medicine, Dong Shin University1,
Jeonnam Development Institute for Korean Traditional Medicine, 756 Gisanri Anyangmyun Jangheunggun Jeonnam 529-8512,
DongWooDang Pharmacyco. 981, Haengwon-ri, Jangheung-eup, Jangheung-gun, jeonnam, Korea3


Objective : The roots of Aconitum species have been believed to cure yang depletion syndrome, kideny-yang deficiency syndrome, and obstruction of qi in the chest syndrome and have been used in traditional Korean medicine mainly for the treatment of musculoskeletal disorders. As they are the substances with toxity, they are processed by using such processing materials as childrens’ urine, Gamdutang, wet-heating. So the purpose of this study is to select most efficient method by evaluating effects of various procesing method on the contents of aconitine.

Method : The contents of aconitine in the Aconitum plantswere determined by high performance liquid chromatography.

Results :

1. Radix Aconiti Kusnezoffii contains twice amount of aconitine than Chun-Oh.

2. Contents of aconitine in Kyungpo-Buja, Buja-Kyungpo, childrens’ urine Buja, heuksoonpyeon are reduced by processing.

3. Content of aconitine in heuksoonpyeon is reduced the most.

Conclusion : Content of aconitine in heuksoonpyeon is reduced the most.

KeyWords : Aconitum plants, Kyungpo-Buja, Radix Aconiti Kusnezoffii, Chun-Oh, Buja-Kyungpo, childrens’ urine Buja, heuksoonpyeon, high performance liquid chromatography



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