Table 1. Changes in the application of Sibjo-tang for long-term use | |||
Application | composition (Herbal name) | weight (g) | Usage |
modified Sibjo-tang | Euphorbia kansui, | 1 | Four herbs are extracted with hot water (100℃) for 150 minutes. |
Euphorbia pekinensis | 1 | ||
Daphne genkwa | 1 | ||
Zizyphus jujuba | 5 | ||
original Sibjo-tang | Euphorbia kansui, | 0.17~0.33 | Take 0.5 to 1.0 grams of powder from the other three herbs in a liquid made by boiling 10 grams of Zizyphus jujuba. |
Euphorbia pekinensis | 0.17~0.33 | ||
Daphne genkwa | 0.17~0.33 | ||
Zizyphus jujuba | 8~10 | ||
Table 2. Age and sex distribution | |||
Age(years) | Sex | Total(%) | |
Male(%) | Female(%) | ||
< 1 | 0 | 1 | 1 |
1-5 | 0 | 0 | 0 |
6-10 | 1 | 2 | 3 |
11-15 | 1 | 0 | 1 |
> 15 | 1 | 1 | 2 |
Total | 3 | 4 | 7(100) |
Table 3. Duration and side effects of Sibjo-tang Administration (SA) | ||||
No. | Sex/Age | Seizure type | SA duration (months) | side effects |
Case1 | M/6 | Atonic seizure | 48 | no |
Case2 | F/38 | 2ndary generalization | 18 | no |
Case3 | M/23 | Atonic seizure | 11 | no |
Case4 | F/<1 | Infantile spasm | 1 | no |
Case5 | F/7 | Simple partial | 20 | no |
Case6 | F/7 | Simple partial | 8 | no |
Case7 | M/13 | Simple partial | 10 | no |
SA, Sibjo-tang Administration |
Table 4. Comparison of seizure frequency before and after Sibjo-tang Administration (SA) | ||||||
No. | Prevalence period up to SA (months) | Combined medication with AED | Seizure numbers for a month before SA | Seizure numbers for a month after SA | SA duration (months) | The latest check (seizure number/periods) |
Case1 | < 1 | - | > 100 | < 40 | 48 | 0/40 M |
Case2 | 39 | - | 4 | 0 | 18 | 0/18 M |
Case3 | > 144 | ○ | > 15 | 1 | 11 | 2/6 M |
Case4 | 5 | ○ | > 90 | 0 | 1 | 0/1 M |
Case5 | < 1 | - | 2 | 0 | 20 | 0/18 M |
Case6 | 11 | - | > 30 | 0 | 8 | 0/1 M |
Case7 | 45 | - | 1 | 0 | 10 | 0/10 M |
SA, Sibjo-tang Administration; AED, anti-epileptic drugs; M, month(s). |
Table 5. Related factors to seizures in the 7 cases | ||||
No. | Seizure type | Frequent indigestion | Easy exhaustion | Inferiority complex |
Case1 | Atonic seizure | ○ | ○ | ○ |
Case2 | 2ndary generalization | ○ | ||
Case3 | Atonic seizure | ○ | ○ | |
Case4 | Infantile spasm | ○ | ○ | |
Case5 | Simple partial | ○ | ○ | ○ |
Case6 | Simple partial | ○ | ○ | ○ |
Case7 | Simple partial | ○ | ○ | ○ |
Total | 100% | 71.4% | 71.4% |
Table 6. Classification of epilepsy seizures by M. Walker et al. | |||
Classifications | Subclassifications | Symptoms | |
Partial seizure | Simple partial | temporal lobe seizure | Strong fear, strong sense of paramnesia, unpleasant smell and taste. |
prefrontal lobe seizure | Unwilling spasm in one arm or leg, head and eyes turning to one side. | ||
parietal lobe seizure | Tingling on one side of the patient's body. | ||
occipital lobe seizure | Second flash in one eye of the patient. | ||
Complex partial | More complex, wider area than simple partial seizures. | Combined with the above simple partial seizures, In severe cases, impaired cognitive function, automatic symptoms persist in behaviors such as crumpling, chewing, running, dancing, undressing, and rambling, but do not remember after recovering consciousness. | |
2ndary generalization | Topical brainwaves diffuse to both hemispheres of the cerebrum. | Warning symptoms (aura) or sudden loss of consciousness, stiffness and collapse with a high-pitched groan, blue in the face, regular shaking in the arms and legs, heavy breathing, foam in the mouth, biting the tongue, or urinating. | |
Generalized seizure | absence seizures | Seizures begin in both hemispheres of the cerebrum, usually suddenly unconscious. | Stop doing for a few seconds and recover after being dazed. |
myoclonic seizure | Very short spastic reflexes occur in the limbs or all over the body, suddenly raising hands or throwing whole body on the floor. |
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